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Trans-AT 聚酮合成酶(PKSs)是一类能够合成大量结构特殊、活性多样的聚酮分子的酶。这些酶中同时存在多种特殊模块或结构域,如β-分支模块、分支结构域和BV氧化结构域等,可在装配线上直接对延伸的聚酮骨架进行修饰,增加产物的结构多样性。然而,在trans-AT PKS的非经典催化过程中,单一模块或功能域的迭代使用过程尤为特殊。
When nitric oxide (NO) binds to heme proteins, it exerts a repulsive trans effect on the proximal ligand, resulting in weakening or rupture of the proximal ligand-iron bond. The general question of wh...
We present several lines of evidence, based on different kinds of observations, and we conclude that it is likely that rotational fission has occurred for a fraction of the known trans-Neptunian objec...
This dissertation examines the molecular mechanisms regulating Rac2 gene expression during cell differentiation and identification of a minimal cis-element required for the induction of Rac2 gene expr...
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
Indus river valley basin in Northwest Indian Himalaya is tectonically unstable, exhibiting a complex topography, landscape relief and varied Quaternary sedimentation. A 422 km transact along the Indus...
Gas phase thermal isomerization rates of trans-stilbene obey the Arrhenius law at T~300 K, indicating that intramolecular vibrational redistribution (IVR) is complete or not restrictive for the reacti...
We present Herschel PACS photometry of 18 Plutinos and determine sizes and albedos for these objects using thermal modeling. We analyze our results for correlations, draw conclusions on the Plutino si...
The hydrolysis process of Ru(III) complex (HL)[trans-RuCl4L(dmso-S)] (L=1-methyl-1,2,4-triazole and dmso-S=S-dimethyl sulfoxide) (1), a potential antitumor complex similar to the well-known antitumor ...
From CCD observations of a fixed and large star field that contained the binary TNO Orcus, we have been able to derive high-precision relative astrometry and photometry of the Orcus system with respec...
The chloroalkenes trans-1-chloro-3,3,3-trifluoropropylene (tCFP) and trans-1,2-dichloroethylene (tDCE) have been proposed as candidate replacements for other compounds in current use that cause concer...
We interpret observations from the Intercontinental Chemical Transport Experiment, Phase B (INTEX-B) in spring 2006 using a global chemical transport model (GEOS-Chem) to evaluate sensitivities of the...
In May 2003, both MODIS aerosol optical depth (AOD) and carbon monoxide (CO) measurements from MOPITT show significant trans-Pacific transport to North America. We apply the global chemical transport ...
The effects of stretching forces on covalently bridged 3-mercaptopropanoic acid molecules between magnetic particles (MPs) and Ag nano-particles (NPs) were studied by surface-enhanced Raman scatterin...

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