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Case Report of Restoration of the Corneal Epithelium in a Patient with Atopic Keratoconjunctivitis Resulting in Amelioration of Ocular Allergic Inflammation
allergic inflammation atopic keratoconjunctivitis conjunctiva corneal ulcer epithelium
2010/11/12
Background: Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement. In vitro studies hav...
Importance of IL-18-Induced Super Th1 Cells for the Development of Allergic Inflammation
allergic inflammation atopic dermatitis bronchial asthma IL-18 super Th1
2010/11/12
Th1 cells, which express IL-18R, produce IFN-γ in response to Ag and IL-2 and increase further production of IFN-γ upon additional IL-18 stimulation. They simultaneously produce Th2 cytokines (IL-9 an...
Subcutaneous Vaccination of Mycobacterium bovis Bacillus Calmette-Guérin Attenuates Allergic Inflammation in a Murine Model of Asthma
asthma CD4+ T cell chemokine Mycobacterium bovis Th1/Th2
2010/11/22
We found that BCG-vaccinated mice had fewer eosinophils in BALF and less severe allergic inflammation. The expression of IL-4 as well as Eotaxin and TARC was down-regulated in the vaccinated mice, whi...
Immunopharmacological Approach to Elucidating the Mechanism of Allergic Inflammation
allergic inflammation allergy anti-allergic drug eosinophil mast cell
2010/11/19
Allergy has now become amongst the commonest disease in the world and the patients are increasing. There have been significant improvements in our understanding of allergic disease and its management....
Serum levels of soluble CD14 in allergic inflammation
asthma atopic dermatitis CD14 inflammation macrophage monocyte
2010/11/29
Monocytes/macrophages have recently been shown to play a significant role in the pathogenesis of allergic diseases. As the level of soluble CD14 (sCD14) in serum is considered a marker of monocyte/mac...