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Prevention of tracheal high-dose tolerance induction by granulocyte-macrophage colony stimulating factor-dependent restoration of antigen-presenting cell function
bronchial asthma eosinophilia T cell tolerance
2010/11/25
The intrusion of airborne allergens into airways elicits eosinophilic inflammation, as represented by bronchial asthma. It has been shown that excessive amounts of allergen in murine trachea lead to a...
Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...