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Study of Physiologic and Immunologic Incompatibilities of Pig to Human Transplantation
Transplantation Xenotransplantation Thrombocytopenia Antibody-mediated rejection
2015/5/22
Solid organ transplantation is limited by available donor allografts. Pig to human transplantation, xenotransplantation, could potentially solve this problem if physiologic and immunologic incompatibi...
The Effect of Natural Adjuvants on Pathological Changes in Sensitized Guinea Pig Lungs
Asthma Lung Pathology
2015/10/10
Background:: Anti-inflammatory effect of natural adjuvants has been reported. Lung inflammation is the most characterized pathological feature in asthma.
Effects of vitamin A and C and melatonin on 3-nitrotyrosine formation in guinea pig heart under lipopolysaccharide-induced stress
Lipopolysaccharide peroxynitrite 3-nitrotyrosine vitamin A vitamin C melatonin
2010/10/14
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O2.-). O2.- can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrot...
Effect Of Pentoxifylline On The Healing Of Guinea Pig Perforated Tympanic Membrane
Guinea pig pentoxifylline tympanic membrane perforation
2009/12/24
Background: Tympanic membrane perforation as a sign of different otologic disorders have multiple causes, for example trauma .Traumatic perforations heal spontaneously in most cases but in large and s...
背景与目的: 探讨再生障碍性贫血(aplastic anemia,AA)患者PIG-A基因外显子2、4、5的突变及粒细胞表面CD55、CD59锚蛋白表达的情况。 材料与方法: 从30例AA患者及20例正常对照组人群外周血提取基因组DNA,采用PCR扩增PIG-A基因外显子2、4、5,再将纯化的PCR产物双向测序检测基因序列;并用流式细胞术检测两组人群外周血粒细胞中CD55、CD59的表达。 结果:...
A Comparative Analysis of Perinatal Development of Barrel Cortex in Rat,Mouse and Guinea Pig Using Acetylcholinesterase Histochemistry
Thalamocortical development barrel cortex rodent and acetylcholinesterase histochemistry
2009/6/30
The role of acetylcholinesterase (AChE) in the developing neocortex was reexamined by comparing its expression in rats, mice and guinea pigs, following the protocol for acetylcholinesterase histochemi...
Effects of KP-496, a Novel Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors, on Contractions Induced by Various Agonists in the Guinea Pig Trachea
antagonist anti-asthmatic drugs asthma leukotriene D4 thromboxane A2
2010/11/19
KP-496 produced parallel rightward shifts of the LTD4 and U46619 concentration-response curves in a concentration-dependent manner. Schild plot analyses of the antagonistic activities of KP-496 demons...
In vitro Comparison of the Intrinsic Activity of Functional Antagonism between β-agonists and Spasmogens in the Guinea-pig Tracheal Muscle
carbachol contraction functional antagonism guinea-pig trachea intrinsic activity potency β-agonists
2010/11/19
Relaxation responses to β-agonists were diminished depending on the extent of carbachol-induced tone in the tracheal muscle. The degree of hyporesponsiveness was greatest in treatment with tulobuterol...