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A new class of molecules called acyldepsipeptides — ADEPs — may provide a new way to attack bacteria that have developed resistance to antibiotics. Researchers at Brown and MIT have discovered a way t...
A Conformational Exploration of Dissymmetric Macrolides Antibiotics
macrolide molecular mechanics conformational analysis and tricarbonyliron
2010/4/22
Conformational analysis of the macrolides from 12 to 22 links was carried out using molecular mechanics. Calculations indicate that each studied macrocycle presents eight families of preferential conf...