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中国科学院动物研究所专利：MONOCLONAL ANTIBODY AGAINST HUMAN PRPC AND USE THEREOF
中国科学院动物研究所 专利 人PrPC蛋白 单克隆抗体
2024/5/31
一种抗人PrPC蛋白的单克隆抗体，能够以靶向方式降低转录因子Twist1的表达水平，并诱导巨噬细胞和NK细胞靶向直肠癌肿瘤细胞。 抗体与西妥昔单抗联合用药的抑瘤效果也优于单用抗体或西妥昔单抗。
Anew genetic variant that protects against Alzheimer’s disease has been identified by an international team led by Harvard Medical School investigators at Massachusetts General Hospital and Massachuse...
In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to rep...
Study offers neurological explanation for how brains bias partisans against new information（图）
大脑 神经学 信息生物学
2023/6/26
People who share a political ideology have more similar ‘neural fingerprints’ of political words and process new information in similar ways, according to a new analysis led by Brown University resear...
Inspired by nature, artificial microtubules can work against a current to transport tiny cargoes（图）
人造微管 逆流工作 血管阻塞 化疗药物
2023/7/7
Like a microscopic bucket brigrade, an artificial microtubule can rapidly transport tiny particles along magnetic stepping stones, delivering them to a precise location even when operating against a s...
Face masks protect against aerosolized toxins from algal blooms, study finds
poisonous alga COVID-19 wear face mask
2021/8/9
Intense blooms of toxic algae are becoming common occurrences along the coast of Florida and elsewhere. Results from a new study found that wearing the face mask everyone has become accustomed to duri...
New gene-editing technique shows promise against sickle cell disease（图）
镰状细胞性贫血 基因编辑技术 一次性治疗
2023/6/21
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri- and postmenopausal women
isoflavone bone estrogen deficiency osteopenia osteoporosis
2018/11/19
Background: Age-related estrogen deficiency leads to accelerated bone resorption. There is evidence that, through selective estrogen receptor modulation, isoflavones may exert beneficial effects again...
A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri- and postmenopausal women
isoflavone, bone, estrogen deficiency, osteopenia, osteoporosis
2018/11/16
Background: Age-related estrogen deficiency leads to accelerated bone resorption. There is evidence that, through selective estrogen receptor modulation, isoflavones may exert beneficial effects again...
Inhibitory Effect of Gamma Irradiation against Cucumber Green Mottle Mosaic Virus
coat protein ionising radiation virus inactivation virion
2018/3/5
Gamma irradiation has been shown to be an effective method of controlling plant bacterial and fungal pathogens, but
data on its effect against plant viruses is limited. A mechanism for the inactivati...
Efficacy of Certain Common Ferns against Red Spider Mite Oligonychus coffeae and Tea Mosquito Bug Helopeltis theivora Infesting Tea
botanicals aqueous extracts acaricidal activity insecticidal activity
2018/3/5
In search for botanicals as an alternative remedy to synthetic chemicals in the pest control of tea plantations, ferns
such as Adiantum raddianum, Asplenium aethiopicum, Cyclosorus interruptus, Dicra...
Biochemists’ Discovery Could Lead to Vaccine Against ‘Flesh-Eating’ Bacteria
Biochemists Vaccine Against Flesh-Eating Bacteria
2016/9/12
One of the world’s longest-running, most comprehensive climate change experiments produced some surprising results. The extensive experiment subjected grassland ecosystems to sixteen possible future c...
Resveratrol-loaded Nanoparticles Induce Antioxidant Activity against Oxidative Stress
Resveratrol Nanoparticle Oxidative Stress β-Lactoglobulin Caco-2 Cell
2016/5/19
Resveratrol acts as a free radical scavenger and a potent antioxidant in the inhibition of numerous reactive oxygen species (ROS). The function of resveratrol and resveratrol-loaded nanoparticles in p...
Stanford scientists resurrect an abandoned drug and find it effective against two human viruses in a lab dish,with potential to fight many more
Stanford scientists abandoned drug two human viruses fight many more
2016/4/13
Viruses have proven to be wily foes. Attempts to fend off viruses causing even the common cold or flu have failed, and new viral outbreaks such as dengue, Ebola or Zika continue to elude drugs.Given t...
Light-activated nanoparticles prove effective against antibiotic-resistant “superbugs”
Light-activated nanoparticles antibiotic-resistant superbugs
2016/2/22
In the ever-escalating evolutionary battle with drug-resistant bacteria, humans may soon have a leg up thanks to adaptive, light-activated nanotherapy developed by researchers at the University of Col...