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Prostaglandin E₂ promotes recovery of hematopoietic stem and progenitor cells after radiation exposure
hematopoiesis radiomitigation radiation
2015/5/21
The hematopoietic system is highly proliferative, making hematopoietic stem and progenitor cells (HSPC) sensitive to radiation damage. Total body irradiation and chemotherapy, as well as the risk of r...
Defining the mechanism of prostaglandin E₂-enhanced hematopoietic stem and progenitor cell homing
Prostaglandin Homing HIF1-alpha
2015/5/21
Hematopoietic stem cell (HSC) transplantation is a lifesaving therapy for a number of hematological disorders. However, to be effective, transplanted HSCs must efficiently “home” to supportive niches ...