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The phrase “survival of the fittest” makes the principle of evolution by natural selection easy to understand — individuals with a trait that adapts them well to their circumstances are more likely to...
Accumulating evidence suggest that genomes are organized non-randomly into complex 3D configurations that vary according to cell type, stage of development, differentiation and disease status. The pri...
In response to different environmental stresses, phosphorylation of eukaryotic initiation factor-2 (eIF2) rapidly reduces protein synthesis, which lowers energy expenditure and facilitates reprogrammi...
Disruptions of the endoplasmic reticulum (ER) cause perturbations in protein folding and result in a cellular condition known as ER stress. ER stress and the accumulation of unfolded protein activate ...

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