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The Structure of Genealogies in the Presence of Purifying Selection: An Effective Coalescent Theory
The Structure Genealogies of Purifying Selection Effective Coalescent Theory
2010/11/15
Purifying selection distorts the structure of genealogies and hence alters the patterns of genetic variation we observe in sequence data. Although these distortions may be common, our understanding of...
The structure of allelic diversity in the presence of purifying selection
The structure allelic diversity presence of purifying selection
2010/11/15
In the absence of selection, the structure of allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecula...
Weak selection, which means a phenotype is slightly advantageous over another, is an important limiting case in evolutionary biology. Recently it has been introduced into evolutionary game theory. In...