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近日，首都医科大学基础医学院李长龙副教授团队在《Gastric Cancer》上发表题为“Sustained exposure toHelicobacter pylori induces immune tolerance bydesensitizing TLR6” 的研究论文。该研究揭示了幽门螺杆菌（Hp）持续感染过程中，通过调控宿主胃上皮细胞TLR6/JNK信号通路抑制IL-8分泌，减少中性粒细...
In vitro comparison of gastric aspirate methods and feeding tube properties on the quantity and reliability of obtained aspirate volume
Gastric Residual Volume Gastric Aspirate Assessment of residual volume
2015/1/19
Gastric residual volume (GRV) is a clinical assessment to evaluate gastric emptying and enteral feeding tolerance. Factors such as the tube size, tube material, tube port configuration, placement of t...
Demographic and Histological Predictors of Survival in Patients With Gastric and Esophageal Carcinoma
Gastric Cancer Esophageal Cancer Histological Factor Demographic Factor Survival
2015/9/30
Background: Little is known about the possible influence of demographic and histological risk factors on the survival of patients with esophageal and gastric cancer.
Application of Smoothing Methods for Determining of the Effecting Factors on the Survival Rate of Gastric Cancer Patients
Proportional Hazards Models Survival Stomach Neoplasms
2015/9/29
Background: Smoothing methods are widely used to analyze epidemiologic data, particularly in the area of environmental health where non-linear relationships are not uncommon. This study focused on thr...
Investigation of Relationship between Hepatitis B Virus and Gastric Adenocarcinoma
Investigation Relationship between Hepatitis Gastric Adenocarcinoma
2015/9/25
Gastric cancer is the second leading cause of cancer-related deaths worldwide1-3 while some genetic and environmental factors such as infectious agents were shown to be linked to carcinogenesis.2 Infe...
Studies on Cinical,Haematological Aspects and Pathological Changes of Gastric Mucosa in Geophagia
studies Cinical,Haematological Aspects Pathological Changes Gastric Mucosa Geophagia
2009/12/7
Geophagia characterized by, severe, anaemia, dwarfism, hypogonadism • and hepatosplenomegaly is sometimes seen in young patients (and children) in Iran. 2) Haematological aspects of the syndrome...
Survival analysis of gastric cancer patients using Cox model: a five year study
Biglarian A Hajizadeh E Kazemnejad A Zali M
2009/11/26
Background: Gastric cancer is the second most common cancer and known as the second cause of death due to cancers worldwide. Adenocarcinoma is the most fatal cancer in Iran and a patient with this kin...
The Effects of Vitamin E on Gastric Ulcers and Gastric Mucosal Barrier in Stress Induced Rats
Vitamin E Stress Gastric mucosal barrier
2009/7/6
Effects of vitamin E on gastric ulcers gastric mucosal barrier were in-vestigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stres...
The Protective Effect of Vitamins E and C on The Gastric Mucosal Barrier in Rats Irradiated With X-Rays
X-rays Gastric mucosal barrier Vitamin E Vitamin C
2009/7/1
The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into fo...
An Immunohistochemical Study of Gastric Neuroendocrine Tumors: Expression of Proliferating Cell Nuclear Antigen and P53 Oncoprotein
Gastric neuroendocrine tumors PCNA p53 oncoprotein
2009/6/30
The aim of this study is to examine expression of Proliferating cell nuclear antigen (PCNA) and p53 oncoprotein in gastric neuroendocrine tumors. 35 gastric neuroendocrine tumors were analyzed for fir...
山东临朐胃癌高发人群和北京人群Lewis血型抗原相关SE基因多态性分析Analysis of Polymorphisms on Lewis Blood Group Antigen Related SE Gene in the Populations in Shandong with High-risk of Gastric Cancer and Beijing
胃癌 Lewis血型抗原 SECRETOR基因 基因多态性
2007/12/30
摘要为探讨宿主的遗传背景和幽门螺杆菌（Helicobacter pylori,H.pylori）相关胃癌的易感性之间的关系，本文采用PCR产物直接测序和PCR-RFLP的方法，检测142例山东临朐县胃癌高发人群个体（包括69例癌症患者和73例非癌个体）和93例北京正常对照个体SE基因多态性的分布特点。结果显示：sew/sew基因型在山东非癌个体和北京人群之间的分布差异具有统计学意义（P＜0.01,...
山东胃癌高低发人群Lewis基因多态性分析Analysis of Lewis Gene Polymorphism in High and Low Incidence Area of Gastric Cancer in Shandong Province
胃癌 高低发人群 Lewis基因多态性
2007/12/30
摘要应用PCR产物直接测序的方法，检测山东省胃癌高发的临朐人群和低发的苍山人群中Lewis基因多态性T59G的分布,旨在探讨山东临朐和苍山地区胃癌发病率显著不同的内在原因，为阐明临朐地区胃癌高发的机制提供实验依据。结果表明,T59G突变个体在临朐和苍山人群中的分布频率分别为34.5%和31.6%，差别无统计学意义，P＞0.05,OR为1.14 （95% CI,0.59~2.19）。提示就此点突变而...
摘要
为探讨一种快速、简便、可靠的胃癌微卫星不稳定性（MSI）检测方法，变性聚丙烯酰胺凝胶电泳-银染法检测28例胃癌12个微卫星位点(D1S548、D1S552、D5S346、TP53、IGFIIR(G)8、IGFIIR(CT)5、TGFßRII(GT)3、TGFßRII(A)10、hMSH3(A)8、hMSH6(G)8、BAX(G)8和Bat26），DHPLC柱温50℃...
COMPARISON OF LEVELS OF NITRIC OXIDE, SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE OF GASTRIC JUICE IN INFECTED AND NON-INFECTED PATIENTS WITH HELICOBACTER PYLORI
Helicobacter pylori nitric oxide oxidative stress superoxide dismutase glutathione peroxidase
2010/2/4
Helicobacter Pylori infection leads to different clinical and pathological outcomes in humans, including chronic gastritis and gastric neoplasia. It has been demonstrated that oxidative stress associa...
THE ROLE OF NITRIC OXIDE IN STRESS-INDUCED GASTRIC DAMAGE IN CHOLESTATIC RATS
Nitnc oxide stress gastric damage
2010/5/7
In this study the effect of nitric oxide synthesis inhibition on stress-induced gastric damage was evaluated in bile duel ligated, sham operated and unoperated rats. Animals were injected intraperiton...