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Simulation-based Parameter Estimation for Complex Models: A Breast Cancer Natural History Modelling Illustration
Simulation-based Parameter Estimation Complex Models Breast Cancer Natural History Modelling Illustration
2015/7/6
Simulation-based parameter estimation offers a powerful means of estimating parameters in complex stochastic models. We illustrate the application of these ideas in the setting of a natural history mo...
A Natural History Model of Stage Progression Applied to Breast Cancer
natural history model stage progression breast cancer SEER tumour growth
2015/7/6
Invasive breast cancer is commonly staged as local, regional or distant disease. We present a stochastic model of the natural history of invasive breast cancer that quantifies (1) the relative rate th...