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Impact of chronic and acute inflammation on extra- and intracellular iron homeostasis
acute phase response C-reactive protein ferroportin hepatocyte hepcidin infancy intra- and extracellular pathogens macrophage pregnancy
2018/11/21
Inflammation has a major impact on iron homeostasis. This review focuses on acute and chronic inflammation as it affects iron trafficking and, as a result, the availability of this essential micronutr...
Surrogate disease markers as substitutes for chronic disease outcomes in studies of diet and chronic disease relations
biomarker qualification diet and health relations surrogate disease markers diet and chronic disease surrogate disease marker qualification
2018/11/20
Surrogate biomarkers for clinical outcomes afford scientific and economic efficiencies when investigating nutritional interventions in chronic diseases. However, valid scientific results are dependent...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/19
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/16
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Chronic fructose substitution for glucose or sucrose in food or beverages has little effect on fasting blood glucose, insulin, or triglycerides: a systematic review and meta-analysis
sugar replacement fructose glucose sucrose insulin triglycerides diabetes body weight
2018/11/15
Background: Conflicting evidence exists on the role of long-term fructose consumption on health. No systematic review has addressed the effect of isoenergetic fructose replacement of other sugars and ...
Eccentric Cycling: A Promising Modality for Patients with Chronic Heart Failure
EXERCISE CARDIAC REHABILITATION OXYGEN UPTAKE EXERCISE REHABILITATION
2018/4/24
Purpose Chronic heart failure (CHF) is characterized by dyspnea and poor exercise tolerance, which decreases aerobic capacity (V˙O2peak), a measure strongly correlated with quality of life and mortali...
Potential Corticomotor Plasticity in Those with and without Chronic Ankle Instability
FIBULARIS LONGUS NEUROMUSCULAR ACTIVITY MOTOR CORTEX TRANSCRANIAL MAGNETIC STIMULATION
2018/4/24
Introduction Quantifying corticomotor alterations is important to understand the neurophysiological mechanisms that likely contribute to the neuromuscular control deficits observed in patients with ch...
Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group
Dietary Reference Intakes chronic disease intake response evidentiary challenges evidence assessments
2018/11/12
Dietary Reference Intakes (DRIs) are used in Canada and the United States in planning and assessing diets of apparently healthy individuals and population groups. The approaches used to establish DRIs...
Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
uraemia immunosuppression lymphopenia mitogens flow cytometry
2016/11/11
Chronic kidney disease alters the immune response in humans and dogs and it is thought to be one of the causes of immunosuppression in cats. Haematological, biochemical, and immunological examinations...
Telehealth methods to deliver dietary interventions in adults with chronic disease: a systematic review and meta-analysis
telehealth diet quality dietary diet fruit vegetables chronic disease
2018/12/19
Background: The long-term management of chronic disease requires the adoption of complex dietary recommendations, which can be facilitated by regular coaching to support behavioral changes. Telehealth...
Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial
blood pressure cardiometabolic health milk protein vascular function dairy whey, caseinate angiotensin-converting enzyme inhibition
2018/12/19
Background: Cardiovascular diseases (CVDs) are the greatest cause of death globally, and their reduction is a key public-health target. High blood pressure (BP) affects 1 in 3 people in the United Kin...
Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease
24-hour urine chronic kidney disease sodium intake spot urine hypertension cardiovascular disease
2018/12/3
Background: Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical an...
Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease
24-hour urine chronic kidney disease sodium intake spot urine hypertension cardiovascular disease
2018/12/13
Background: Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical an...
Treatment of protein-energy malnutrition in chronic nonmalignant disorders
chronic renal failure rheumatoid arthritis elderly
2016/6/14
Protein-energy malnutrition (PEM) is common
in connection with chronic disease and is associated with
increased morbidity and mortality. Because the risk of PEM is
related to the degree of illness,...
Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes
Vitamin E heart rate variability catecholamines
2016/6/13
Type 2 diabetes is associated with elevated oxidative
stress and declines in antioxidant defense. The disease is
also characterized by an imbalance in the ratio of cardiac sympathetic
to parasympat...