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Impact of chronic and acute inflammation on extra- and intracellular iron homeostasis
acute phase response C-reactive protein ferroportin hepatocyte hepcidin infancy intra- and extracellular pathogens macrophage pregnancy
2018/11/21
Inflammation has a major impact on iron homeostasis. This review focuses on acute and chronic inflammation as it affects iron trafficking and, as a result, the availability of this essential micronutr...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/19
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease
24-hour urine chronic kidney disease sodium intake spot urine hypertension cardiovascular disease
2018/12/3
Background: Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical an...
Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease
24-hour urine chronic kidney disease sodium intake spot urine hypertension cardiovascular disease
2018/12/13
Background: Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical an...
Treatment of protein-energy malnutrition in chronic nonmalignant disorders
chronic renal failure rheumatoid arthritis elderly
2016/6/14
Protein-energy malnutrition (PEM) is common
in connection with chronic disease and is associated with
increased morbidity and mortality. Because the risk of PEM is
related to the degree of illness,...
Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes
Vitamin E heart rate variability catecholamines
2016/6/13
Type 2 diabetes is associated with elevated oxidative
stress and declines in antioxidant defense. The disease is
also characterized by an imbalance in the ratio of cardiac sympathetic
to parasympat...
Acute effects of different nutritional supplements on symptoms and functional capacity in patients with chronic obstructive pulmonary disease
Nutrition exercise COPD
2016/6/12
Use of nutritional supplements in depleted patients
with chronic obstructive pulmonary disease (COPD) requires
optimization between positive effects on outcome and potential
acute adverse effects o...
Are dietary patterns useful for understanding the role of diet in chronic disease?
dietary patterns chronic disease
2016/6/12
The application of epidemiologic methods to nutrition is
fraught with complications because of the highly interrelated
nature of dietary exposures. For this reason, it is often difficult to
separat...
Effects of chronic alcohol treatment on the synthesis, sialylation, and disposition of nascent apolipoprotein E by peritoneal macrophages of rats
Chronic ethanol feeding macrophages apolipoprotein E glycosylation sialylation sialic acid content
2016/6/7
Background: Plasma apolipoprotein (apo) E, a sialoprotein,
plays an important role in reverse cholesterol transport. Previously,
we showed that chronic alcohol consumption impairs glycosylation
of ...
Human beings evolved consuming a diet that contained
about equal amounts of n23 and n26 essential fatty acids.
Over the past 100–150 y there has been an enormous increase in the
consumption of n26 ...
Cereals, legumes, and chronic disease risk reduction: evidence from epidemiologic studies
Dietary fiber whole grains legumes
2016/6/1
There is growing evidence that cereals and
legumes play important roles in the prevention of chronic diseases.
Early epidemiologic studies of these associations focused
on intake of dietary fiber r...
Potential mechanisms of metabolic imprinting that lead to chronic disease
early nutrition chronic disease obesity
2016/5/30
This review synthesizes a subset of human epidemiologic
and experimental animal studies that suggest that
early nutrition affects susceptibility to chronic diseases in adulthood.
These studies prov...
Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance
Creatine Nitrate Creatine nitrate Nutrition Supplementation Exercise performance
2016/5/16
Background:Creatine monohydrate (CrM) and nitrate are popular supplements for improving exercise performance; yet have not been investigated in combination. We performed two studies to determine the s...
Role of the microenvironment in chronic pancreatitis and pancreatic cancer
Chronic pancreatitis exocrine pancreas inflammatory bowel disease pancreatic ductal adenocarcinoma enzyme acini pancreatic stellate cell activation
2017/2/22
Chronic pancreatitis, an inflammatory disease of the exocrine pancreas, has been reported to be a major risk factor for the development of pancreatic ductal adenocarcinoma. Evidence from pre-clinical ...
Frequency of Peripheral Arterial Disease in Patients With Chronic Venous Insufficiency
Peripheral Vascular Disease Venous Insufficiency Risk Factors Ankle Brachial Index Leg Ulcer
2016/1/26
Background: It is estimated that about 15% (10% - 30% in most of the studies) of the total adult population has some aspects of the Chronic Venous Insufficiency (CVI). Frequency of the Peripheral Arte...